recoñecemento – Debe indicar a debida atribución de autoría, fornecer unha ligazón á licenza e indicar se se realizaron cambios. Pode facer isto de calquera forma razoable, mais non nunha forma que indique que quen posúe a licenza apoia ou subscribe o seu uso da obra.
https://creativecommons.org/licenses/by/3.0CC BY 3.0 Creative Commons Attribution 3.0 truetrue
Pés de foto
Engada unha explicación dunha liña do representa este ficheiro
Este ficheiro contén información adicional, probablemente engadida pola cámara dixital ou polo escáner usado para crear ou dixitalizar a imaxe. Se o ficheiro orixinal foi modificado, poida que algúns detalles non se reflictan no ficheiro modificado.
Autor
Fengyun Sun and Mary Ann Handel *
Título curto
A Mutation in Mtap2 Is Associated with Arrest of Mammalian Spermatocytes before the First Meiotic Division
Título da imaxe
In spite of evolutionary conservation of meiosis, many of the genes that control mammalian meiosis are still unknown. We report here that the ENU-induced repro4 mutation, identified in a screen to uncover genes that control mouse meiosis, causes failure of spermatocytes to exit meiotic prophase I via the G2/MI transition. Major events of meiotic prophase I occurred normally in affected spermatocytes and known regulators of the meiotic G2/MI transition were present and functional. Deep sequencing of mutant DNA revealed a mutation located in an intron of the Mtap2 gene, encoding
Comentario do ficheiro JPEG
In spite of evolutionary conservation of meiosis, many of the genes that control mammalian meiosis are still unknown. We report here that the ENU-induced repro4 mutation, identified in a screen to uncover genes that control mouse meiosis, causes failure of spermatocytes to exit meiotic prophase I via the G2/MI transition. Major events of meiotic prophase I occurred normally in affected spermatocytes and known regulators of the meiotic G2/MI transition were present and functional. Deep sequencing of mutant DNA revealed a mutation located in an intron of the Mtap2 gene, encoding
Data e hora de dixitalización
10 de xaneiro de 2011 ás 14:52
Software utilizado
Microsoft® Office Word 2007
Data e hora de modificación do ficheiro
2 de outubro de 2012 ás 21:07
Data da última modificación dos metadatos
2 de outubro de 2012 ás 21:07
Palabras clave
meiosis; spermatogenesis; microtubule-associated protein