Pilar D’Ocon Navaza

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Pilar D’Ocon Navaza
Pilardoconvanaza.jpg
Nacemento1957
 Betanzos
NacionalidadeEspaña
Alma máterUniversidade de Valencia
Ocupaciónfarmacóloga
editar datos en Wikidata ]

Pilar D’Ocon Navaza, nada en Betanzos en 1957, é unha catedrática galega de farmacoloxía da Universidade de Valencia.

Traxectoria[editar | editar a fonte]

É doutora en Farmacia pola Universidade de Valencia, catedrática de farmacoloxía e directora do Máster “Investigación e Uso Racional do Medicamento” (2006-presente) integrado no programa de doutoramento de biomedicina e farmacia con mención de calidade.

Foi secretaria (1987-1988) e vicedecana (1988-1990) da Facultade de Farmacia da Universidade de Valencia, membro da Comisión de Investigación (1986-1991, 2001-2003) e da Comisión Técnica de elaboración dos novos Plans de Estudos da mesma universidade (1991-1993). Tamén formou parte de diversas comisións do Departamento de Farmacoloxía e pertence á Xunta de Centro desta facultade.

Obra[editar | editar a fonte]

  • Miquel R, Gisbert R, Serna E., Pérez-Vizcaino F, Anselmi E, Noguera MA, Ivorra MD, D’Ocon P. Acute and chronic captopril, but not prazosin nor nifedipine, normalize alterations in adrenergic intracellular Ca2+ handling observed in the mesenteric arterial tree of spontaneously hypertensive rats J Pharmacol Exp Ther, 313: 359-367, 2005.
  • Miquel R, Ali Z, D’Ocon P, McGrath JC, Daly CI, A 3D image análisis method for studying fluorescent drug binding in segments of blood vessel wall Molecular Imaging, 4: 1-13, 2005
  • Ivorra M.D., Valiente M., Martínez S., Madrero Y., Noguera M.A., Cassels B.K., Sobarzo E., D’Ocon P., 8-NH2 Boldine an antagonist of 1A- and 1B-adrenoceptors without affinity for the 1D subtype: structural requirements of aporphines at 1 adrenoceptor subtypes Planta Med, 71: 897-903, 2005
  • Martí, D., Miquel, R., Ziani, K., Gisbert, R., Ivorra, MD, Anselmi, E., Moreno, L., Villagrasa, V., Barettino D., D’Ocon P Correlation between mRNA levels and functional role of 1-adrenoceptor subtypes in arteries: evidence of 1L as a functional isoform of the 1A -adrenoceptor. Am J Physiol Heart Circ Physiol , 289, H1923-1932, 2005
  • Nuñez, C., Victor, VM, Tur, R., Álvarez-Barrientos, A., Moncada, S., Esplugues, JV, D’Ocon P. Discrepancies between nitroglycerin and NO-releasing drugs on mitochondrial oxygen consumption, vasoactivity and the release of NO Cir Res, 97: 1063-1069, 2005
  • Esplugues JV, Rocha M., Nuñez C., Boscá I., Ibiza, S., Herance JR., Ortega A., Serrador JM., D’Ocon P., Victor VM. Complex I dysfunction and tolerance to nitroglycerin: an approach based on mitochondrial-targeted antioxidants Circ. Res. 99 (11): 1067-1075, 2006
  • Agüero J, Almenar L, D’Ocon P, Oliver E, Montó F, Moro J, Castelló A, Rueda J, Martínez-Dolz L, Sánchez-Lazaro I, Montero JA , Correlation Between Beta-Adrenoceptors and G-Protein-Coupled Receptor Kinases in Pretransplantation Heart Failure Transplant Proc 40, 3014-3016, 2008
  • Oliver E, Martí D, Montó F, Flacco N, Moreno L, Barettino D, Ivorra MD, D’Ocon P , The impact of 1-adrenoceptors up-regulation accompanied by the impairment of -adrenergic vasodilatation in hypertension J. Pharmacol Exp. Ther., 328, 982-990, 2009
  • VM. Victor, C Nuñez, P D’Ocon, C Taylor, JV Esplugues and S Moncada Regulation of oxygen distribution in tissues by endothelial nitric oxide Circ Res 104 (10):1178-1183, 2009
  • J. Agüero, L. Almenar, P. D’Ocon, E. Oliver, F. Montó, J. Rueda, D. Vicente, L. Martínez-Dolz, A. Salvador Myocardial and peripheral lymphocytic transcriptomic dissociation of -adrenoceptors and G protein–coupled receptor kinases in heart transplantation J. Heart Lung Transplant. 28(11):1166-1171, 2009
  • E. Oliver, E. Rovira, F. Montó, C. Valldecabres, R. Julve, V. Muedra, N. Ruiz, D. Barettino, P. D’Ocon β-Adrenoceptor and GRK3 expression in human lymphocytes is related to blood pressure and urinary albumin excretion. J Hypertens (en prensa)