Membrana basilar

Membrana basilar
Sección a ravés do órgano de Corti, na que se mostra a membrana basilar
Sección transversal da cóclea.
Latín	membrana basilaris ductus cochlearis
Gray's	pág.1056
MeSH	Basilar+membrane

A membrana basilar situada na cóclea do oído interno é un elemento estrutural ríxido que separa os dous tubos ou escalas cheas de líquidos que corren en espiral ao longo da cóclea, que son a escala media e a escala timpática (ver figura).

Estrutura

The basilar membrane is a pseudo-resonant structure that, like strings on an instrument, varies in width and stiffness. The "string" of the basilar membrane is not a set of parallel strings, as in a guitar, but a long structure that has different properties (width, stiffness, mass, damping, and the dimensions of the ducts that it couples to) at different points along its length. The motion of the basilar membrane is generally described as a traveling wave. The parameters of the membrane at a given point along its length determine its characteristic frequency (CF), the frequency at which it is most sensitive to sound vibrations. The basilar membrane is widest (0.42–0.65 mm) and least stiff at the apex of the cochlea, and narrowest (0.08–0.16 mm) and most stiff at the base. High-frequency sounds localize near the base of the cochlea (near the round and oval windows), while low-frequency sounds localize near the apex.

Función

Sinusoidal drive through the oval window (top) causes a traveling wave of fluid–membrane motion. A modeled snapshot of fluid streamlines is shown. The wavelength is long compared to the duct height near the base, in what is called the long-wave region, and short (0.5 to 1.0 mm in typical observations) near the place where the displacement and velocity are maximized, just before cutoff, in the short-wave region.

Separación endolinfa/perilinfa

The fluids in these two tubes, the endolymph and the perilymph are very different chemically, biochemically, and electrically. Therefore they are kept strictly separated. This separation is the main function of Reissner's membrane (between scala vestibuli and scala media), and it is also the function of tissue held by the basilar membrane such as the inner and outer sulcus cells (shown in yellow) and the reticular lamina of the organ of Corti (shown in magenta). For the organ of Corti the basilar membrane is permeable to perilymph. Here the border between endolymph and perilymph occurs at the reticular lamina, the endolymph side of the organ of Corti.

Base para as células sensoriais

The basilar membrane is also the base for the sensory cells of hearing, the hair cells that are equipped with "Stereocilia". There are approximately 15,000 hair cells in each human ear (see figure). This function as base of the sensory cells gave the basilar membrane its name, and it is again present in all land vertebrates. Due to its location, the basilar membrane places the hair cells in a position where they are adjacent to both the endolymph and the perilymph, which is a precondition of hair cell function.

Dispersión de frecuencias

A third, evolutionarily younger, function of the basilar membrane is strongly developed in the cochlea of most mammalian species and weakly developed in some bird species: the dispersion of incoming sound waves to separate frequencies spatially. In brief, the membrane is tapered and it is stiffer at one end than at the other. Furthermore, sound waves travelling to the far, "floppier" end of the basilar membrane have to travel through a longer fluid column than sound waves travelling to the nearer, stiffer end. Each part of the basilar membrane, together with the surrounding fluid, can therefore be thought of as a "mass-spring" system with different resonant properties: high stiffness and low mass, hence high resonant frequencies at the near end, and low stiffness and high mass, hence low resonant frequencies, at the far end. This causes sound input of a certain frequency to vibrate some locations of the membrane more than other locations. As shown in experiments by Nobel Prize laureate Georg von Békésy, high frequencies lead to maximum vibrations at the basal end of the cochlear coil, where the membrane is narrow and stiff, and low frequencies lead to maximum vibrations at the apical end of the cochlear coil, where the membrane is wider and more compliant. This "place–frequency map" can be described quantitatively by the Greenwood function and its variants.

Sound-driven vibrations travel as waves along this membrane, along which, in humans, lie about 3,500 inner hair cells spaced in a single row. Each cell is attached to a tiny triangular frame. The 'hairs' are minute processes on the end of the cell, which are very sensitive to movement. When the vibration of the membrane rocks the triangular frames, the hairs on the cells are repeatedly displaced, and that produces streams of corresponding pulses in the nerve fibers, which are transmitted to the auditory pathway. The outer hair cells feed back energy to amplify the traveling wave, by up to 65 dB at some locations.

Galería

• 
  Sección lon xitudinal da cóclea.
• 
  Piso do conduto coclear.
• 
  Limbo espiral e membrana basilar.
• 
  Sección a través do órgano espiral de Corti (ampliada).
• 
  A membrana reticular e estruturas subxacentes.

Véxase tamén

Outros artigos

• Célula de Deiters

Ligazóns externas

• Auditory Neuroscience | The Ear con varias animacións que mostran o movemento da membrana basilar en varias condicións de estímulos
• Functional anatomy of the inner ear: con moitas imaxes, animacións, e explicacións moi concisas e funcionais
• Basilar Membrane Simulator Vídeo e textos sobre a estimulación da membrana basilar
• The role of the basilar membrane in sound reception: boa explicación e diagramas